MDPI - Publisher of Open Access Journals

13 pages, 562 KiB

Open AccessArticle

Intraoperative and Postoperative Outcomes of Pfannenstiel and Midline Skin Incisions in Placenta Accreta Spectrum Disorders: Single-Center Experience

by Hulya Kandemir, Emine Kirtis, Gul Alkan Bulbul, Selen Dogan, Inanc Mendilcioglu, Cem Yasar Sanhal, Mehmet Sakinci and Nasuh Utku Dogan

Medicina 2024, 60(7), 1102; https://doi.org/10.3390/medicina60071102 - 5 Jul 2024

Abstract

Background: We compared Pfannenstiel and midline skin incisions for cesarean hysterectomy in women with confirmed Placenta Accreta Spectrum Disorders. Aims: A retrospective cohort study was conducted to evaluate the outcomes of Pfannenstiel and midline skin incisions in women undergoing cesarean section hysterectomy for [...] Read more.

Background: We compared Pfannenstiel and midline skin incisions for cesarean hysterectomy in women with confirmed Placenta Accreta Spectrum Disorders. Aims: A retrospective cohort study was conducted to evaluate the outcomes of Pfannenstiel and midline skin incisions in women undergoing cesarean section hysterectomy for suspected placenta accreta at Akdeniz University Hospital between January 2010 and February 2022. Histopathological confirmation was obtained for all cases. Demographic, perioperative, and postoperative data, along with neonatal outcomes, were extracted from the hospital’s electronic database. Possible complaints related to the incision site or other issues (e.g., vaginal dryness or sexual life) were identified through telephone interviews. Subjects were stratified into Pfannenstiel and midline incision cohorts, with subsequent data comparison. Results: Data from 67 women with a histopathologically confirmed PAS diagnosis were analyzed. Of these, 49 (73.1%) underwent Pfannenstiel incision, and 18 (26.9%) had a midline skin incision. Incisions were based on the surgeon’s experience. Pfannenstiel incision was more common in antepartum hemorrhage, preoperative hemorrhage, and emergency surgery (p = 0.02, p = 0.014, p = 0.002, respectively). Hypogastric artery ligation occurred in 30 cases (61.2%) in the Pfannenstiel group but none in the midline group. Cosmetic dissatisfaction and sexual problems were more prevalent in the midline group (p < 0.05, all). Preoperative and postoperative blood parameters, transfused blood products, and neonatal outcomes were similar between the two groups. Conclusions: Relaparotomy, bladder injury, blood loss, and need for blood transfusion were more prevalent in the Pfannenstiel group, while greater dissatisfaction with the incision was observed in the midline incision group. Midline incision seems to be more favorable in patients with Placenta Accreta Spectrum (PAS). Patients may be informed regarding the worse cosmetic outcomes and possible sexual problems related to vaginal dryness when midline laparotomy is planned. But before opting for a Pfannenstiel incision, patients should receive comprehensive information regarding the potential risks of relaparotomy and bladder injury. Full article

(This article belongs to the Section Obstetrics and Gynecology)

► Show Figures

Figure 1

25 pages, 3439 KiB

Open AccessArticle

Split-Step Galerkin FE Method for Two-Dimensional Space-Fractional CNLS

by Xiaogang Zhu, Yaping Zhang and Yufeng Nie

Fractal Fract. 2024, 8(7), 402; https://doi.org/10.3390/fractalfract8070402 - 5 Jul 2024

Abstract

In this paper, we study a split-step Galerkin finite element (FE) method for the two-dimensional Riesz space-fractional coupled nonlinear Schrödinger equations (CNLSs). The proposed method adopts a second-order split-step technique to handle the nonlinearity and FE approximation to discretize the fractional derivatives in [...] Read more.

In this paper, we study a split-step Galerkin finite element (FE) method for the two-dimensional Riesz space-fractional coupled nonlinear Schrödinger equations (CNLSs). The proposed method adopts a second-order split-step technique to handle the nonlinearity and FE approximation to discretize the fractional derivatives in space, which avoids iteration at each time layer. The analysis of mass conservative and convergent properties for this split-step FE scheme is performed. To test its capability, some numerical tests and the simulation of the double solitons intersection and plane wave are carried out. The results and comparisons with the algorithm combined with Newton’s iteration illustrate its effectiveness and advantages in computational efficiency. Full article

(This article belongs to the Special Issue Recent Advances in Fractional Differential Equations and Their Applications, 2nd Edition)

► Show Figures

Figure 1

8 pages, 2852 KiB

Open AccessCase Report

ADEM as an Initial Presentation of SLE: A Case Report

by Yousuf Sherwani, Ayham Alsaab and Mohan Sengodan

Reports 2024, 7(3), 53; https://doi.org/10.3390/reports7030053 - 5 Jul 2024

Abstract

Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disorder of the white matter. The pathophysiology is thought to be immune-mediated as in most cases the condition follows an infection or triggering incident. More recent literature has demonstrated that there may be a link [...] Read more.

Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disorder of the white matter. The pathophysiology is thought to be immune-mediated as in most cases the condition follows an infection or triggering incident. More recent literature has demonstrated that there may be a link between autoimmune conditions and ADEM. Here we present a case of ADEM in a middle-aged woman with systemic lupus erythematosus that recovered well after treatment with corticosteroids and rituximab. Full article

(This article belongs to the Section Allergy/Immunology)

► Show Figures

Figure 1

27 pages, 5728 KiB

Open AccessArticle

ID-Det: Insulator Burst Defect Detection from UAV Inspection Imagery of Power Transmission Facilities

by Shangzhe Sun, Chi Chen, Bisheng Yang, Zhengfei Yan, Zhiye Wang, Yong He, Shaolong Wu, Liuchun Li and Jing Fu

Drones 2024, 8(7), 299; https://doi.org/10.3390/drones8070299 - 5 Jul 2024

Abstract

The global rise in electricity demand necessitates extensive transmission infrastructure, where insulators play a critical role in ensuring the safe operation of power transmission systems. However, insulators are susceptible to burst defects, which can compromise system safety. To address this issue, we propose [...] Read more.

The global rise in electricity demand necessitates extensive transmission infrastructure, where insulators play a critical role in ensuring the safe operation of power transmission systems. However, insulators are susceptible to burst defects, which can compromise system safety. To address this issue, we propose an insulator defect detection framework, ID-Det, which comprises two main components, i.e., the Insulator Segmentation Network (ISNet) and the Insulator Burst Detector (IBD). (1) ISNet incorporates a novel Insulator Clipping Module (ICM), enhancing insulator segmentation performance. (2) IBD leverages corner extraction methods and the periodic distribution characteristics of corners, facilitating the extraction of key corners on the insulator mask and accurate localization of burst defects. Additionally, we construct an Insulator Defect Dataset (ID Dataset) consisting of 1614 insulator images. Experiments on this dataset demonstrate that ID-Det achieves an accuracy of 97.38%, a precision of 97.38%, and a recall rate of 94.56%, outperforming general defect detection methods with a 4.33% increase in accuracy, a 5.26% increase in precision, and a 2.364% increase in recall. ISNet also shows a 27.2% improvement in Average Precision (AP) compared to the baseline. These results indicate that ID-Det has significant potential for practical application in power inspection. Full article

(This article belongs to the Special Issue Resilient UAV Autonomy and Remote Sensing: 2nd Edition)

32 pages, 8070 KiB

Open AccessArticle

A Condition-Monitoring Methodology Using Deep Learning-Based Surrogate Models and Parameter Identification Applied to Heat Pumps

by Pieter Rousseau and Ryno Laubscher

Math. Comput. Appl. 2024, 29(4), 52; https://doi.org/10.3390/mca29040052 - 5 Jul 2024

Abstract

Online condition-monitoring techniques that are used to reveal incipient faults before breakdowns occur are typically data-driven or model-based. We propose the use of a fundamental physics-based thermofluid model of a heat pump cycle combined with deep learning-based surrogate models and parameter identification in [...] Read more.

Online condition-monitoring techniques that are used to reveal incipient faults before breakdowns occur are typically data-driven or model-based. We propose the use of a fundamental physics-based thermofluid model of a heat pump cycle combined with deep learning-based surrogate models and parameter identification in order to simultaneously detect, locate, and quantify degradation occurring in the different components. The methodology is demonstrated with the aid of synthetically generated data, which include the effect of measurement uncertainty. A “forward” neural network surrogate model is trained and then combined with parameter identification which minimizes the residuals between the surrogate model results and the measured plant data. For the forward approach using four measured performance parameters with 100 or more measured data points, very good prediction accuracy is achieved, even with as much as 20% noise imposed on the measured data. Very good accuracy is also achieved with as few as 10 measured data points with noise up to 5%. However, prediction accuracy is reduced with less data points and more measurement uncertainty. A “backward” neural network surrogate model can also be applied directly without parameter identification and is therefore much faster. However, it is more challenging to train and produce less accurate predictions. The forward approach is fast enough so that the calculation time does not impede its application in practice, and it can still be applied if some of the measured performance parameters are no longer available, due to sensor failure for instance, albeit with reduced accuracy. Full article

(This article belongs to the Special Issue Current Problems and Advances in Computational and Applied Mechanics (AfriComp6))

► Show Figures

Figure 1

20 pages, 2884 KiB

Open AccessSystematic Review

Cultural Heritage as a Didactic Resource through Extended Reality: A Systematic Review of the Literature

by Andrea Dordio, Eva Lancho, María José Merchán and Pilar Merchán

Multimodal Technol. Interact. 2024, 8(7), 58; https://doi.org/10.3390/mti8070058 - 5 Jul 2024

Abstract

Extended reality, which encompasses virtual, augmented, and mixed reality, emerges as an important didactic resource, offering great potential to bring heritage closer to the educational environment. Heritage education is a challenge for today’s society, contributing to cultural and social development. Therefore, the aim [...] Read more.

Extended reality, which encompasses virtual, augmented, and mixed reality, emerges as an important didactic resource, offering great potential to bring heritage closer to the educational environment. Heritage education is a challenge for today’s society, contributing to cultural and social development. Therefore, the aim of this systematic review is to analyze documents related to heritage in education through extended reality. The search was conducted using Scopus and Web of Sciences databases, allowing for an international search. We excluded any document that was not a scientific article published in a journal. A total of 52 documents were analyzed, all of which were open-access articles. Preliminary results indicate that virtual reality and augmented reality are utilized in education to work with architectural, historical, archaeological, and musical heritage. Extended reality has been applied in all the stages of the education system, and in formal and non-formal settings, thereby demonstrating its versatility. These experiences increase motivation and academic performance in comparison to less innovative methodologies, which is in line with other studies on this topic. In conclusion, extended reality has the potential to make a significant impact on education, particularly when combined with heritage. The creation of multidisciplinary groups will enhance research in the near future. Full article

► Show Figures

Figure 1

23 pages, 517 KiB

Open AccessArticle

Public Key Protocols from Twisted-Skew Group Rings

by Javier de la Cruz, Edgar Martínez-Moro, Steven Muñoz-Ruiz and Ricardo Villanueva-Polanco

Cryptography 2024, 8(3), 29; https://doi.org/10.3390/cryptography8030029 - 5 Jul 2024

Abstract

This article studies some algebraic structures known as twisted-skew group rings in the context of public key cryptography. We first present some background related to these structures to then specifically introduce particular twisted-skew group rings and show how to utilize them as the [...] Read more.

This article studies some algebraic structures known as twisted-skew group rings in the context of public key cryptography. We first present some background related to these structures to then specifically introduce particular twisted-skew group rings and show how to utilize them as the underlying algebraic structure to build cryptographic protocols. We closely follow an incremental-like methodology to construct these protocols by putting parts together. As as result, we first introduce a key-agreement protocol and then generalize it to a group key-agreement protocol. We then proceed to construct a probabilistic public key encryption from our two-party key agreement and, finally, introduce a key-encapsulation mechanism from a well-known generic construction applied to probabilistic public encryption. Furthermore, we provide an in-depth security analysis for each cryptographic construction under new related algebraic assumptions and supply a proof-of-concept implementation for various candidate chosen groups. Full article

15 pages, 836 KiB

Open AccessArticle

Exposure of Zebrafish Embryos to Morphine and Cocaine Induces Changes in the Levels of Dopamine and of Proteins Related to the Reward Pathway

by Andres Angel Calderon-Garcia, Mercedes Sánchez-Barba and Veronica Gonzalez-Nunez

Fishes 2024, 9(7), 268; https://doi.org/10.3390/fishes9070268 - 5 Jul 2024

Abstract

Morphine, a drug of abuse used to treat moderate-to-severe pain, elicits its actions by binding to the opioid receptors. Cocaine is an example of a recreational drug that inhibits dopamine reuptake. The molecular effects of morphine and cocaine have been described in different [...] Read more.

Morphine, a drug of abuse used to treat moderate-to-severe pain, elicits its actions by binding to the opioid receptors. Cocaine is an example of a recreational drug that inhibits dopamine reuptake. The molecular effects of morphine and cocaine have been described in different specific brain regions. However, the systemic outcome of these drugs on the whole organism has not been fully addressed. The aim of this study is to analyse the global effects of morphine (10 μM) and cocaine (15 μM) in the expression of proteins related to the reward pathway. Zebrafish embryos were exposed to these drugs from 5 hpf (hours post-fertilisation) to 6 dpf (days post-fertilisation). Dopamine levels were determined by ELISA, and the expression of Fos proteins, Creb, its activated form p-Creb and tyrosine hydroxylase (Th) were examined by Western blot. Both drugs decreased Th levels at 72 hpf and 6 dpf and modified the expression of Fos family members, pCreb and Creb in a time-dependent manner. Morphine and cocaine exposure differentially modified dopamine levels in 72 hpf and 6 dpf zebrafish embryos. Our results indicate that drugs of abuse modify the expression of several proteins and molecules related to the activation of the reward pathway. Full article

(This article belongs to the Section Physiology and Biochemistry)

10 pages, 490 KiB

Open AccessArticle

Counting Conditions on Newborn Bloodspot Screening Panels in Australia and New Zealand

by Natasha Heather, Ronda F. Greaves, Kaustuv Bhattacharya, Lawrence Greed, James Pitt, Carol Wai-Kwan Siu, Mark de Hora, Ricky Price, Enzo Ranieri, Tiffany Wotton and Dianne Webster

Int. J. Neonatal Screen. 2024, 10(3), 47; https://doi.org/10.3390/ijns10030047 - 5 Jul 2024

Abstract

A greater number of screened conditions is often considered to equate to better screening, whereas it may be due to conditions being counted differently. This manuscript describes a harmonised Australasian approach to listing target conditions found on bloodspot screening panels. Operational definitions for [...] Read more.

A greater number of screened conditions is often considered to equate to better screening, whereas it may be due to conditions being counted differently. This manuscript describes a harmonised Australasian approach to listing target conditions found on bloodspot screening panels. Operational definitions for target disorders and incidental findings were developed and applied to disorder lists. A gap analysis was performed between five, state-based Australian newborn screening programme disorder lists and the single national New Zealand and state-level Californian versions. Screening panels were found to be broadly similar. Gap analysis with Californian data reflected differences in jurisdictional approval (for example, haemoglobinopathies and lysosomal disorders not being recommended in Australasia). Differences amongst Australasian panels reflected varied the timeframes recommended in order to implement newly approved disorders, as well as decisions to remove previously screened disorders. A harmonised approach to disorder counting is essential to performing valid comparisons of newborn bloodspot screening panels. Full article

17 pages, 1468 KiB

Open AccessArticle

A Study on the Design of Knee Exoskeleton Rehabilitation Based on the RFPBS Model

by Qiujian Xu, Junrui Li, Nan Jiang, Xinran Yuan, Siqi Liu, Dan Yang, Xiubo Ren, Xiaoyu Wang, Mingyi Yang, Yintong Liu and Peng Zhang

Biomimetics 2024, 9(7), 410; https://doi.org/10.3390/biomimetics9070410 - 5 Jul 2024

Abstract

The gait rehabilitation knee exoskeleton is an advanced rehabilitative assistive device designed to help patients with knee joint dysfunction regain normal gait through training and activity support. This paper introduces a design framework based on the process knowledge representation method to optimize the [...] Read more.

The gait rehabilitation knee exoskeleton is an advanced rehabilitative assistive device designed to help patients with knee joint dysfunction regain normal gait through training and activity support. This paper introduces a design framework based on the process knowledge representation method to optimize the design and control efficiency of the knee exoskeleton. This framework integrates knowledge of design objects and processes, specifically including requirements, functions, principle work areas, and the representation and multi-dimensional dynamic mapping of the Behavior–Structure (RFPBS) matrix, achieving multi-dimensional dynamic mapping of the knee exoskeleton. This method incorporates biomechanical and physiological knowledge from the rehabilitation process to more effectively simulate and support gait movements during rehabilitation. Research results indicate that the knee rehabilitation exoskeleton design, based on the RFPBS process knowledge representation model, accomplishes multi-dimensional dynamic mapping, providing a scientific basis and effective support for the rehabilitation of patients with knee joint dysfunction. Full article

(This article belongs to the Special Issue Biomimicry for Optimization, Control, and Automation: 2nd Edition)

30 pages, 32286 KiB

Open AccessReview

Various Antibacterial Strategies Utilizing Titanium Dioxide Nanotubes Prepared via Electrochemical Anodization Biofabrication Method

by Wuzhi Wang, Hanpeng Liu, Zilin Guo, Zijun Hu, Kefeng Wang, Yujia Leng, Caideng Yuan, Zhaoyang Li and Xiang Ge

Biomimetics 2024, 9(7), 408; https://doi.org/10.3390/biomimetics9070408 - 5 Jul 2024

Abstract

Currently, titanium and its alloys have emerged as the predominant metallic biomaterials for orthopedic implants. Nonetheless, the relatively high post-operative infection rate (2–5%) exacerbates patient discomfort and imposes significant economic costs on society. Hence, urgent measures are needed to enhance the antibacterial properties [...] Read more.

Currently, titanium and its alloys have emerged as the predominant metallic biomaterials for orthopedic implants. Nonetheless, the relatively high post-operative infection rate (2–5%) exacerbates patient discomfort and imposes significant economic costs on society. Hence, urgent measures are needed to enhance the antibacterial properties of titanium and titanium alloy implants. The titanium dioxide nanotube array (TNTA) is gaining increasing attention due to its topographical and photocatalytic antibacterial properties. Moreover, the pores within TNTA serve as excellent carriers for chemical ion doping and drug loading. The fabrication of TNTA on the surface of titanium and its alloys can be achieved through various methods. Studies have demonstrated that the electrochemical anodization method offers numerous significant advantages, such as simplicity, cost-effectiveness, and controllability. This review presents the development process of the electrochemical anodization method and its applications in synthesizing TNTA. Additionally, this article systematically discusses topographical, chemical, drug delivery, and combined antibacterial strategies. It is widely acknowledged that implants should possess a range of favorable biological characteristics. Clearly, addressing multiple needs with a single antibacterial strategy is challenging. Hence, this review proposes systematic research into combined antibacterial strategies to further mitigate post-operative infection risks and enhance implant success rates in the future. Full article

(This article belongs to the Special Issue Functional Biomimetic Materials and Devices for Biomedical Applications: 3rd Edition)

► Show Figures

Figure 1

42 pages, 2978 KiB

Open AccessReview

Fabrication Strategies for Bioceramic Scaffolds in Bone Tissue Engineering with Generative Design Applications

by Bilal Cinici, Sule Yaba, Mustafa Kurt, Huseyin C. Yalcin, Liviu Duta and Oguzhan Gunduz

Biomimetics 2024, 9(7), 409; https://doi.org/10.3390/biomimetics9070409 - 5 Jul 2024

Abstract

The aim of this study is to provide an overview of the current state-of-the-art in the fabrication of bioceramic scaffolds for bone tissue engineering, with an emphasis on the use of three-dimensional (3D) technologies coupled with generative design principles. The field of modern [...] Read more.

The aim of this study is to provide an overview of the current state-of-the-art in the fabrication of bioceramic scaffolds for bone tissue engineering, with an emphasis on the use of three-dimensional (3D) technologies coupled with generative design principles. The field of modern medicine has witnessed remarkable advancements and continuous innovation in recent decades, driven by a relentless desire to improve patient outcomes and quality of life. Central to this progress is the field of tissue engineering, which holds immense promise for regenerative medicine applications. Scaffolds are integral to tissue engineering and serve as 3D frameworks that support cell attachment, proliferation, and differentiation. A wide array of materials has been explored for the fabrication of scaffolds, including bioceramics (i.e., hydroxyapatite, beta-tricalcium phosphate, bioglasses) and bioceramic–polymer composites, each offering unique properties and functionalities tailored to specific applications. Several fabrication methods, such as thermal-induced phase separation, electrospinning, freeze-drying, gas foaming, particle leaching/solvent casting, fused deposition modeling, 3D printing, stereolithography and selective laser sintering, will be introduced and thoroughly analyzed and discussed from the point of view of their unique characteristics, which have proven invaluable for obtaining bioceramic scaffolds. Moreover, by highlighting the important role of generative design in scaffold optimization, this review seeks to pave the way for the development of innovative strategies and personalized solutions to address significant gaps in the current literature, mainly related to complex bone defects in bone tissue engineering. Full article

(This article belongs to the Special Issue Functional Biomimetic Materials and Devices for Biomedical Applications: 3rd Edition)

15 pages, 1853 KiB

Open AccessArticle

Distributed Broadcast Control of Multi-Agent Systems Using Hierarchical Coordination

by Mahmudul Hasan, Mohammad Khalid Saifullah, Md Abdus Samad Kamal and Kou Yamada

Biomimetics 2024, 9(7), 407; https://doi.org/10.3390/biomimetics9070407 - 5 Jul 2024

Abstract

Broadcast control (BC) is a bio-inspired coordination technique for a swarm of agents in which a single coordinator broadcasts an identical scalar signal to all performing agents without discrimination, and the agents make appropriate moves towards the agents’ collective optimal state without communicating [...] Read more.

Broadcast control (BC) is a bio-inspired coordination technique for a swarm of agents in which a single coordinator broadcasts an identical scalar signal to all performing agents without discrimination, and the agents make appropriate moves towards the agents’ collective optimal state without communicating with one another. The BC technique aims to accomplish a globally assigned task for which BC utilizes a stochastic optimization algorithm to coordinate a group of agents. However, the challenge intensifies as the system becomes larger: it requires a larger number of agents, which protracts the converging time for a single coordinator-based BC model. This paper proposes a revamped version of BC model, which assimilates distributed multiple coordinators to control a larger multi-agent system efficiently in a pragmatic manner. Precisely, in this hierarchical BC scheme, the distributed multiple sub-coordinators broadcast the identical feedback signal to the agents, which they receive from the global coordinator to accomplish the coverage control task of the ordinary agents. The dual role of sub-coordinators is manipulated by introducing weighted averaging of the gradient estimation under the stochastic optimization mechanism. The potency of the proposed model is analyzed with numerical simulation for a coverage control task, and various performance aspects are compared with the typical BC schemes to demonstrate its practicability and performance improvement. Particularly, the proposed scheme shows the same convergence with about 30% less traveling costs, and the near convergence is reached by only about one-third of iteration steps compared to the typical BC. Full article

(This article belongs to the Special Issue Learning from Nature—2nd Edition: Bionics in Design Practice)

► Show Figures

Figure 1

12 pages, 623 KiB

Open AccessCommunication

Suitability of XRF for Routine Analysis of Multi-Elemental Composition: A Multi-Standard Verification

by Riccardo Fedeli, Luigi Antonello Di Lella and Stefano Loppi

Methods Protoc. 2024, 7(4), 53; https://doi.org/10.3390/mps7040053 - 5 Jul 2024

Abstract

This study investigated the suitability of X-ray fluorescence (XRF) analysis for routine multi-elemental composition analysis, checking its analytical capabilities by measuring a wide array of certified reference materials of soil and plant origin. A portable XRF analyzer was used to evaluate 32 soil [...] Read more.

This study investigated the suitability of X-ray fluorescence (XRF) analysis for routine multi-elemental composition analysis, checking its analytical capabilities by measuring a wide array of certified reference materials of soil and plant origin. A portable XRF analyzer was used to evaluate 32 soil and 12 plant standard materials, using both the Soil and Geochem mode, with sequential beams, allowing the detection of a wide range of elements. Recovery rates were calculated by comparing XRF measurements with certified values, and their correlations were verified through the Spearman coefficient. The results demonstrated the reliability of XRF measurements for soil samples, with a large number of elements showing a good or very good recovery and strong correlations with certified values. For plant samples, XRF largely overestimated the certified values, but the strong statistically significant correlations for almost all tested elements allowed us to correct this systematic bias, using the reported median value for dividing the value obtained via XRF. The Geochem mode emerged as more reliable for a larger number of elements. It was concluded that XRF may be a suitable alternative to ICP-MS in routine multi-elemental composition analysis. Full article

(This article belongs to the Section Biochemical and Chemical Analysis & Synthesis)

39 pages, 1023 KiB

Open AccessReview

Occupational Chemical Exposure and Health Status of Wildland Firefighters at the Firefront: A Systematic Review

by Tatiana Teixeira, Liliana Almeida, Isabel Dias, João Santos Baptista, Joana Santos, Mário Vaz and Joana Guedes

Safety 2024, 10(3), 60; https://doi.org/10.3390/safety10030060 - 5 Jul 2024

Abstract

Wildland firefighting represents a physically and mentally demanding endeavour fraught with various risk factors. The primary aim of this study is to delineate occupational chemical exposure within the firefighting work environment on the firefront and its implications for firefighters’ health status. A systematic [...] Read more.

Wildland firefighting represents a physically and mentally demanding endeavour fraught with various risk factors. The primary aim of this study is to delineate occupational chemical exposure within the firefighting work environment on the firefront and its implications for firefighters’ health status. A systematic literature review was conducted utilising diverse keyword combinations across Scopus, Web of Science, Academic Search Complete, and ScienceDirect databases. Only English-language journal articles, real-world monitoring reports, and studies featuring samples of firefighters were considered for inclusion. Forty-one studies were analysed, with 26 focusing on firefighters’ occupational exposure to chemical agents during wildland firefighting and 15 addressing the health impairments of wildland firefighting activities. Polycyclic aromatic hydrocarbons (PAHs), VOCs, and particulates emerged as the most prevalent chemical agents in the exposure profiles of frontline firefighters. They were shown to be the main incidents of cardiovascular disease, respiratory disease, and work-related cancer. The rigorous demands of wildland firefighting have been demonstrated to significantly impact firefighter health, resulting in a notable prevalence of fatalities and illnesses. Given that an elevated number of health issues are common in this occupation, adopting advanced assessment technologies is imperative. Full article

(This article belongs to the Topic New Research in Work-Related Diseases, Safety and Health)

16 pages, 526 KiB

Open AccessReview

Review of Integrated Management Systems to Re-Engineer Existing Nonconformances Troubleshooting System

by Matshidiso Moso and Oludolapo Akanni Olanrewaju

Safety 2024, 10(3), 58; https://doi.org/10.3390/safety10030058 - 5 Jul 2024

Abstract

Total quality management (TQM) is a strategic philosophy that has adopted kaizen activities which drives the business to carry out activities effectively to yield the best desired output, hence, a profitable organization. The kaizen philosophy acts as a catalyst in productivity rate and [...] Read more.

Total quality management (TQM) is a strategic philosophy that has adopted kaizen activities which drives the business to carry out activities effectively to yield the best desired output, hence, a profitable organization. The kaizen philosophy acts as a catalyst in productivity rate and integrated management systems (IMS) which results in drastic improvements. When the nonconformity arises within the process, the accuracy of the problem solving determines quality of preventive action, therefore the preventive action should be accompanied by the opportunity of improvement from the raised nonconformance. This research seeks to add more knowledge and upgrade technology of problem-solving models relating to the integrated management systems by examining various troubleshooting models for problem solving and preventive action related to quality nonconformances, safety incidents and engineering breakdowns. Hence, the aim of this research is for troubleshooting model technique enhancement for issues related to process engineering, quality management systems and occupational health and safety by creating a model which analyses kaizen projects from the corrective and preventive action analysis of nonconformances. The proposed troubleshooting model was developed using lean techniques and risk rating tools; it was then applied to the case study company for simulation and the outcomes resulted in the closure of nonconformances and continual improvement of future projects. The proposed model is more advantageous to the manufacturing industries seeking to improve their Corrective Action and Preventive Action (CAPA) systems. Full article

17 pages, 1406 KiB

Open AccessArticle

Subjective Effects of Using a Passive Upper Limb Exoskeleton for Industrial Textile Workers

by Edda Maria Capodaglio, Federica Amitrano, Armando Coccia, Vittorio Gabba, Gaetano Pagano, Giovanni D’Addio and Monica Panigazzi

Safety 2024, 10(3), 59; https://doi.org/10.3390/safety10030059 - 5 Jul 2024

Abstract

Industrial wool textile production exposes workers mainly to the biomechanical loading of the shoulder joint. In this work context, which is characterized by poor machine ergonomics, exposure to biomechanical risk factors, and variable work organization, exoskeletons could facilitate work processes or could be [...] Read more.

Industrial wool textile production exposes workers mainly to the biomechanical loading of the shoulder joint. In this work context, which is characterized by poor machine ergonomics, exposure to biomechanical risk factors, and variable work organization, exoskeletons could facilitate work processes or could be a valuable means to protect workers from overuse injuries. Field evaluation is essential to verify the suitability of specific devices and their acceptance by users. As part of a pilot study, we examined the short-term subjective effects of a passive Arm-Support Exoskeleton (ASE) on workers performing repetitive overhead tasks. In a textile factory, eight workers participated in the study, answering questionnaires after carrying out a work session with (ASE) and without an exoskeleton (FREE). Participants had been using the Paexo exoskeleton for

4.2 \pm 5.8

months (min 0–max 12). Subjective evaluations were collected regarding the workload (NASA-TLX) and relief (Borg’s CR10 scale) obtained from the use of the exoskeleton, satisfaction (Quebec User Evaluation of Satisfaction with Assistive Technology (QUEST)), usability (System Usability Scale (SUS)), and opinions on the ergonomics of the device (Ergonomics questionnaire). Workers reported a high workload (NASA

7.2 \pm 1.0

) and assessed a 46% reduction in effort on the CR10 in ASE conditions compared to FREE. They expressed high satisfaction with most characteristics of the ASE (100% satisfied with durability and effectiveness), high level of usability (62% of scores above 80, out of a maximum score of 100), and ergonomics of the device (

88 \pm 12

, out of a maximum score of 110). In addition to the objective effects (electromyography (EMG) reduction) already demonstrated in a previous publication, these qualitative results demonstrate a positive perception by textile workers regarding the effectiveness, usability, and suitability of the exoskeleton. The adoption of ASE in the textile industry appears beneficial in the short term, but the impact associated with individual variables and long-term effects remains to be explored. Full article

(This article belongs to the Special Issue Advances in Ergonomics and Safety)

30 pages, 11216 KiB

Open AccessReview

Carbon Dots for Future Prospects: Synthesis, Characterizations and Recent Applications: A Review (2019–2023)

by Habtamu Fekadu Etefa, Aster Aberra Tessema and Francis Birhanu Dejene

C 2024, 10(3), 60; https://doi.org/10.3390/c10030060 - 5 Jul 2024

Abstract

Carbon dots (CDs) have emerged as a promising class of carbon-based nanomaterials due to their unique properties and versatile applications. Carbon dots (CDs), also known as carbon quantum dots (CQDs) or graphene quantum dots (GQDs), are nanoscale carbon-based materials with dimensions typically less [...] Read more.

Carbon dots (CDs) have emerged as a promising class of carbon-based nanomaterials due to their unique properties and versatile applications. Carbon dots (CDs), also known as carbon quantum dots (CQDs) or graphene quantum dots (GQDs), are nanoscale carbon-based materials with dimensions typically less than 10 nanometers. They exhibit intriguing optical, electronic, and chemical properties, making them attractive for a wide range of applications, including sensing, imaging, catalysis, and energy conversion, among many others. Both bottom-up and top-down synthesis approaches are utilized for the synthesis of carbon dots, with each method impacting their physicochemical characteristics. Carbon dots can exhibit diverse structures, including amorphous, crystalline, or hybrid structures, depending on the synthesis method and precursor materials used. CDs have diverse chemical structures with modified oxygen, polymer-based, or amino groups on their surface. These structures influence their optical and electronic properties, such as their photoluminescence, bandgap, and charge carrier mobility, making them tunable for specific applications. Various characterization methods such as HRTEM, XPS, and optical analysis (PL, UV) are used to determine the structure of CDs. CDs are cutting-edge fluorescent nanomaterials with remarkable qualities such as biocompatibility, low toxicity, environmental friendliness, high water solubility, and photostability. They are easily adjustable in terms of their optical properties, making them highly versatile in various fields. CDs find applications in bio-imaging, nanomedicine, drug delivery, solar cells, photocatalysis, electrocatalysis, and other related areas. Carbon dots hold great promise in the field of solar cell technology due to their unique properties, including high photoluminescence, high carbon quantum yield (CQY), and excellent charge separation. Full article

► Show Figures

Graphical abstract

16 pages, 3929 KiB

Open AccessArticle

Integrated In Vivo and In Vitro Evaluation of a Powder-to-Hydrogel, Film-Forming Polymer Complex Base with Tissue-Protective and Microbiome-Supportive Properties

by Daniel Banov, Guiyun Song, Zahraa Foraida, Oksana Tkachova, Oleksandr Zdoryk and Maria Carvalho

Gels 2024, 10(7), 447; https://doi.org/10.3390/gels10070447 - 5 Jul 2024

Abstract

The study aimed to perform a comprehensive in vitro and in vivo evaluation of a newly developed, patent-pending, powder-to-hydrogel, film-forming polymer complex base, which possesses tissue-protective and microbiome-supportive properties, and to compare its characteristics with poloxamer 407. The study used a combination of [...] Read more.

The study aimed to perform a comprehensive in vitro and in vivo evaluation of a newly developed, patent-pending, powder-to-hydrogel, film-forming polymer complex base, which possesses tissue-protective and microbiome-supportive properties, and to compare its characteristics with poloxamer 407. The study used a combination of in vitro assays, including tissue viability and cell migration, and in vivo wound healing evaluations in male diabetic mice. Microbiome dynamics at wound sites were also analyzed. The in vitro assays demonstrated that the polymer complex base was non-cytotoxic and that it enhanced cell migration over poloxamer 407. In vivo, the polymer complex base demonstrated superior wound healing capabilities, particularly in combination with misoprostol and phenytoin, as evidenced by the reduced wound area and inflammation scores. Microbiome analysis revealed favorable shifts in bacterial populations associated with the polymer complex base-treated wounds. The polymer complex base demonstrates clinical significance in wound care, potentially offering improved healing, safety and microbiome support. Its transformative properties and efficacy in drug delivery make it a promising candidate for advanced wound care applications, particularly in chronic wound management. Full article

(This article belongs to the Special Issue Hydrogels for Therapeutic Delivery: Current Developments and Future Directions)

► Show Figures

Figure 1

18 pages, 2769 KiB

Open AccessArticle

Development and Characterization of Hybrid Meat Analogs from Whey Protein-Mushroom Composite Hydrogels

by Ramdattu Santhapur, Disha Jayakumar and David Julian McClements

Gels 2024, 10(7), 446; https://doi.org/10.3390/gels10070446 - 5 Jul 2024

Abstract

There is a need to reduce the proportion of animal-derived food products in the human diet for sustainability and environmental reasons. However, it is also important that a transition away from animal-derived foods does not lead to any adverse nutritional effects. In this [...] Read more.

There is a need to reduce the proportion of animal-derived food products in the human diet for sustainability and environmental reasons. However, it is also important that a transition away from animal-derived foods does not lead to any adverse nutritional effects. In this study, the potential of blending whey protein isolate (WPI) with either shiitake mushroom (SM) or oyster mushroom (OM) to create hybrid foods with enhanced nutritional and physicochemical properties was investigated. The impact of OM or SM addition on the formation, microstructure, and physicochemical attributes of heat-set whey protein gels was therefore examined. The mushroom powders were used because they have relatively high levels of vitamins, minerals, phytochemicals, and dietary fibers, which may provide nutritional benefits, whereas the WPI was used to provide protein and good thermal gelation properties. A variety of analytical methods were used to characterize the structural and physicochemical properties of the WPI-mushroom hybrids, including confocal microscopy, particle electrophoresis, light scattering, proximate analysis, differential scanning calorimetry, thermogravimetric analysis, dynamic shear rheology, textural profile analysis, and colorimetry. The charge on whey proteins and mushroom particles went from positive to negative when the pH was raised from 3 to 9, but whey protein had a higher isoelectric point and charge magnitude. OM slightly increased the thermal stability of WPI, but SM had little effect. Both mushroom types decreased the lightness and increased the brownness of the whey protein gels. The addition of the mushroom powders also decreased the hardness and Young’s modulus of the whey protein gels, which may be because the mushroom particles acted as soft fillers. This study provides valuable insights into the formation of hybrid whey protein-mushroom products that have desirable physiochemical and nutritional attributes. Full article

(This article belongs to the Special Issue Properties and Structure of Plant-Based Emulsion Gels)

► Show Figures

Graphical abstract

15 pages, 4466 KiB

Open AccessArticle

Degradable Gel for Temporary Plugging in High Temperature Reservoir and Its Properties

by Fan Yang, Jinhua Liu, Renjing Ji, Xiaorong Yu, Huan Yang and Gaoshen Su

Gels 2024, 10(7), 445; https://doi.org/10.3390/gels10070445 - 5 Jul 2024

Abstract

Although various degradable gel materials have been developed for temporary plugging in oil fields, they often degrade too quickly in high-temperature environments. To address this issue, an unstable crosslinker was synthesized to prepare a high-temperature degradable gel. This gel does not degrade excessively [...] Read more.

Although various degradable gel materials have been developed for temporary plugging in oil fields, they often degrade too quickly in high-temperature environments. To address this issue, an unstable crosslinker was synthesized to prepare a high-temperature degradable gel. This gel does not degrade excessively fast at high temperatures. Temperature and crosslinker concentration are the primary factors influencing gel degradation time, followed by monomer and initiator concentrations. Increased temperature and decreased crosslinker concentration both reduce degradation time, which can be adjusted within the range of 90–130 °C by varying the crosslinker concentration. The molecular structure and thermal stability of the degradable gel were analyzed using FTIR, ¹³C NMR, and TG. Furthermore, the viscoelastic properties, compressive performance, plugging performance, and core damage performance of the gel were evaluated. Within the test range of 0.1–1000 Pa, the storage modulus is higher than the loss modulus. The gel prepared at 130 °C exhibited a compressive stress of 0.25 MPa at 50% strain. The plugging pressure of the gel in sand-filled tubes with varying permeabilities (538.2–2794.1 mD) exceeded 15 MPa while maintaining a core damage rate below 5%. SEM analysis indicated that the degradation mechanism of the gel may involve the collapse of its three-dimensional network structure due to the hydrolysis of amide groups in the crosslinker. The viscosity of the degradation liquid was below 11 mPa·s, enabling it to be brought back to the surface with the formation fluid without the need for further breaking operations. Full article

(This article belongs to the Special Issue Gels in the Oil Field)

► Show Figures

Figure 1

14 pages, 2980 KiB

Open AccessArticle

Optimization of Extraction Parameters to Enhance the Antioxidant Properties of Pyrus spinosa Fruit Extract

by Konstantina Kotsou, Anna Papagiannoula, Theodoros Chatzimitakos, Vassilis Athanasiadis, Eleni Bozinou, Athanassios I. Sfougaris and Stavros I. Lalas

Beverages 2024, 10(3), 56; https://doi.org/10.3390/beverages10030056 - 5 Jul 2024

Abstract

Pyrus spinosa (PS), also known as wild pear, is an indigenous species to the Mediterranean basin. It has attracted interest for its potential use in the food and beverage industries due to its antioxidant properties. This research aims to develop an antioxidant-rich PS [...] Read more.

Pyrus spinosa (PS), also known as wild pear, is an indigenous species to the Mediterranean basin. It has attracted interest for its potential use in the food and beverage industries due to its antioxidant properties. This research aims to develop an antioxidant-rich PS fruit extract by optimizing the extraction parameters. More specifically, through a comprehensive study of the extraction parameters (including extraction duration, temperature, and ethanol concentration), the optimal conditions were determined that can achieve the highest antioxidant properties. High-Performance Liquid Chromatography (HPLC) was employed for the identification and quantitation of the polyphenolic compounds present in PS fruits. The optimized extraction conditions significantly enhanced the antioxidant properties of the extract, with the total polyphenol content increasing by up to 345% (reaching a value of 50.97 mg gallic acid equivalents per g of dry weight in the optimum sample), total flavonoid content by up to 273%, and ascorbic acid content by up to 653%. Furthermore, the antioxidant capacity of the extracts increased by 2356% (by FRAP method) and 1622% (by the DPPH method), with varying extraction parameters. These findings highlight the importance and the effectiveness of optimizing the extraction parameters in order to increase the antioxidant properties of PS fruit extract. Based on these findings, PS extracts can be further utilized in the food and beverage industries to develop new products that will benefit from the antioxidant properties. Full article

► Show Figures

Figure 1

19 pages, 2048 KiB

Open AccessArticle

Contrasting Patterns of Fungal and Bacterial Endophytes Inhabiting Temperate Tree Leaves in Response to Thinning

by Beiping Liu, Chunhuan Li, Xiuhai Zhao, Chunyu Zhang, Xinyi He, Laiye Qu and Naili Zhang

J. Fungi 2024, 10(7), 470; https://doi.org/10.3390/jof10070470 - 5 Jul 2024

Abstract

The phyllosphere is an important but underestimated habitat for a variety of microorganisms, with limited knowledge about leaf endophytes as a crucial component of the phyllosphere microbiome. In this study, we investigated the mechanisms of communities and co-occurrence networks of leaf endophytes in [...] Read more.

The phyllosphere is an important but underestimated habitat for a variety of microorganisms, with limited knowledge about leaf endophytes as a crucial component of the phyllosphere microbiome. In this study, we investigated the mechanisms of communities and co-occurrence networks of leaf endophytes in response to forest thinning in a temperate forest. As we expected, contrasting responses of fungal and bacterial endophytes were observed. Specifically, the diversity of leaf endophytic fungi and the complexity of their co-occurrence networks increased significantly with thinning intensity, whereas the complexity of endophytic bacterial co-occurrence networks decreased. In particular, microbiota inhabiting damaged leaves seem to be more intensively interacting, showing an evident fungi–bacteria trade-off under forest thinning. In damaged leaves, besides the direct effects of thinning, thinning-induced changes in neighbor tree diversity indirectly altered the diversity of leaf fungal and bacterial endophytes via modifying leaf functional traits such as leaf dry matter content and specific leaf area. These findings provide new experimental evidence for the trade-offs between leaf endophytic fungi and bacteria under the different magnitudes of deforestation, highlighting their dependence on the presence or absence of leaf damage. Full article

(This article belongs to the Special Issue Fungal Communities in Various Environments)

Recent Articles

Open Access Journals

Highly Accessed Articles

Latest Books

News

Blog Posts

Topics

Selected Special Issues

Selected Collections

Journals by Subject

Further Information

Guidelines

MDPI Initiatives

Follow MDPI